RNA Details
Disease Name
chronic kidney disease
Tissue
kidney
RNA Symbol
let-7i-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
NA
Pathway
MTOR SIGNALING PATHWAY
PubMed ID
Title
Mesenchymal Stem Cells Attenuate Renal Fibrosis via Exosomes-Mediated Delivery of microRNA Let-7i-5p Antagomir
Year
2021
Function
Exosomal anti-let-7i-5p from mesenchymal stem cells-derived exerts anti-fibrotic effects in TGF-beta1-induced fibrogenic responses in kidney tubular epithelial cells cells in vitro as well as in unilateral ureteral obstruction-induced renal fibrosis model in vivo.